EPH FUMARATE MECHANISM OF ACTION AND THERAPEUTIC POTENTIAL

Ept fumarate operates by inhibiting the enzyme prolyl hydroxylase domain possessed proteins (PHD), which are involved in the regulation read more of hypoxia-inducible factor 1α (HIF-1α). This inhibition leads to the stabilization and upregulation of HIF-1α, a transcription factor that regulates the expression of genes involved in cellular adapta